Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX4 | Q9NPH5 | 20/20 | 0.61 |
| ▸ | CYBB | P04839 | 2/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | NOX5 | Q96PH1 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14931788 | 0.87 | NOX4 (0.69) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL29523661 | 0.87 | NOX4 (0.69) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL29523734 | 0.83 | NOX4 (0.72) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL14931655 | 0.83 | NOX4 (0.72) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL14931735 | 0.83 | NOX4 (0.72) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL29523003 | 0.83 | NOX4 (0.72) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL29523627 | 0.78 | NOX4 (0.58) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL14931576 | 0.78 | NOX4 (0.58) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL14931658 | 0.77 | NOX4 (0.50) | NOX4CYBBNOX1CYP3A4NOX5 | |
| SCHEMBL2218961 | 0.77 | NOX4 (0.69) | NOX4CYBBNOX1CYP3A4NOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2776027-B1 | NADPH OXIDASE 4 INHIBITORS AND USE THEREOF | GENKYOTEX SUISSE SA (CH) | 2017-06-07 | — | — | EP | disclosed |