Biphenyl

Biphenyl

SCHEMBL1894418

C1CCC(C2CCCCC2)CC1.O=C(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.57
RAB9A P51151 2/20 0.57
POLB P06746 2/20 0.49
ELANE P08246 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.45
FAAH O00519 1/20 0.44
GAA P10253 1/20 0.44
NPC1 O15118 1/20 0.43
PKM P14618 1/20 0.43
EPHX2 P34913 1/20 0.43
METAP2 P50579 2/20 0.42
METAP1 P53582 1/20 0.42
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL23214149 0.88 ALDH1A1 (0.53) ALDH1A1RAB9APOLBELANESMN1; SMN2
Cyclohexylamine SCHEMBL27712726 0.85 ALDH1A1 (0.54) ALDH1A1RAB9APOLBELANESMN1; SMN2
SCHEMBL248211 0.82 ALDH1A1 (0.51) ALDH1A1RAB9APOLBELANESMN1; SMN2
SCHEMBL26545208 0.82 ELANE (0.63) ALDH1A1RAB9APOLBELANESMN1; SMN2
SCHEMBL1353554 0.81 ALDH1A1 (0.54) ALDH1A1RAB9APOLBELANESMN1; SMN2
SCHEMBL9353461 0.81 TDP1 (0.54) ALDH1A1ELANESMN1; SMN2
SCHEMBL9241160 0.81 TDP1 (0.54) ALDH1A1ELANESMN1; SMN2
SCHEMBL9353455 0.81 TDP1 (0.54) ALDH1A1ELANESMN1; SMN2
SCHEMBL18073 0.81 TDP1 (0.54) ALDH1A1ELANESMN1; SMN2
SCHEMBL27352197 0.81 TDP1 (0.54) ALDH1A1ELANESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9371437-B2 Polycarbonate plates with improved flame resistance COVESTRO DEUTSCHLAND AG (DE) 2016-06-21 US disclosed
US-20120213982-A1 POLYCARBONATE PLATES WITH IMPROVED FLAME RESISTANCE BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-08-23 US disclosed
US-20110112226-A1 Products with improved flame resistance BAYER MATERIALSCIENCE AG (DE) 2011-05-12 US disclosed
US-6835797-B2 Reacting a dihydroxyaryl compound with a diaryl carbonate to obtain a melt; flash evaporation of the monohydroxyaryl compound; heating the melt under vacuum; and repeating the steps BAYER AKTIENGESELLSCHAFT (DE) 2004-12-28 US disclosed
US-20040103717-A1 Process for the production of polycarbonate which is damaged to a particularly small extent by oxygen BAYER AKTIENGESELLSCHAFT (DE) 2004-06-03 US disclosed
US-20020137874-A1 Process for producing oligocarbonates COVESTRO DEUTSCHLAND AG (DE) 2002-09-26 US disclosed