Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.31 |
| ▸ | FNTA | P49354 | 1/20 | 0.31 |
| ▸ | FNTB | P49356 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1496096 | 0.81 | IDH1 (0.43) | TP53TSPO | |
| SCHEMBL1495933 | 0.67 | AVPR1A (0.42) | DRD2TP53 | |
| SCHEMBL1496069 | 0.65 | AVPR1A (0.42) | DRD3 | |
| SCHEMBL2704306 | 0.64 | IDH1 (0.41) | TSPO | |
| SCHEMBL2629001 | 0.62 | IDH1 (0.37) | — | |
| SCHEMBL8597653 | 0.59 | GNAI3 (0.57) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL8597657 | 0.59 | GNAI3 (0.57) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL19414059 | 0.58 | GNAI3 (0.72) | GNAI3GNAO1GNAI1 | |
| SCHEMBL11539085 | 0.58 | GNAI3 (0.72) | GNAI3GNAO1GNAI1 | |
| SCHEMBL1933069 | 0.58 | GNAI3 (0.72) | GNAI3GNAO1GNAI1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |