Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 7/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.43 |
| ▸ | HTR3B | O95264 | 4/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 6/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6068632 | 0.74 | HTR3A (0.51) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL932525 | 0.70 | HRH4 (0.45) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL934301 | 0.70 | HRH4 (0.49) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL1248367 | 0.70 | HTR3A (0.43) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL2068821 | 0.69 | HTR3A (0.46) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL16741177 | 0.68 | HTR3A (0.56) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL1284202 | 0.66 | HRH4 (0.44) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL82036 | 0.65 | HTR3A (0.55) | HTR3AHTR3EHTR3BHTR3DHTR3C | |
| SCHEMBL16451233 | 0.65 | GAA (0.47) | HTR3AKDM4EALDH1A1 | |
| SCHEMBL16134879 | 0.64 | CYP1A2 (0.57) | HTR3AHTR3EHTR3BHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | disclosed |