Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9952967 | 0.99 | NAMPT (0.53) | NAMPTMAPT | |
| SCHEMBL15378984 | 0.90 | KDM4E (0.53) | NAMPTMAPT | |
| SCHEMBL15377371 | 0.88 | NAMPT (0.51) | NAMPTMAPT | |
| SCHEMBL10212166 | 0.88 | NAMPT (0.52) | NAMPTMAPT | |
| SCHEMBL9953722 | 0.86 | MAPT (0.62) | NAMPTMAPT | |
| SCHEMBL15377987 | 0.86 | PTGDR2 (0.56) | NAMPT | |
| SCHEMBL9953316 | 0.86 | PTGDR2 (0.56) | NAMPT | |
| SCHEMBL15383449 | 0.86 | NAMPT (0.53) | NAMPTMAPT | |
| SCHEMBL15378641 | 0.86 | PTGDR2 (0.56) | NAMPT | |
| SCHEMBL18945927 | 0.86 | NAMPT (0.47) | NAMPTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2661428-B1 | QUINOXALINES AND AZA-QUINOXALINES AS CRTH2 RECEPTOR MODULATORS | MERCK SHARP & DOHME (US) | 2017-06-07 | — | — | EP | disclosed |