Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 2/20 | 0.39 |
| ▸ | QPCT | Q16769 | 3/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18946168 | 0.81 | GRM5 (0.39) | OGAQPCTGRM5KITDYRK1A | |
| SCHEMBL25251508 | 0.79 | OGA (0.39) | OGAQPCTGRM5KITDYRK1A | |
| SCHEMBL3186168 | 0.75 | OGA (0.35) | OGAQPCTGRM5KITDYRK1A | |
| SCHEMBL27046657 | 0.74 | GRM5 (0.36) | OGAQPCTGRM5PIK3C3 | |
| SCHEMBL260041 | 0.74 | CLK4 (0.38) | QPCTGRM5PIK3C3 | |
| SCHEMBL3188485 | 0.74 | PIK3C3 (0.38) | OGAQPCTGRM5DYRK1AKEAP1 | |
| Hydrochloric Acid SCHEMBL1799130 | 0.73 | CLK4 (0.37) | QPCTGRM5PIK3C3 | |
| SCHEMBL729971 | 0.70 | NAMPT (0.41) | OGAQPCTKEAP1PIK3C3PIK3CD | |
| SCHEMBL24570174 | 0.68 | NAMPT (0.40) | OGAQPCTKEAP1PIK3C3PIK3CD | |
| SCHEMBL16582016 | 0.68 | ALDH1A1 (0.41) | QPCTKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017093544-A1 | ALKYNYL PHOSPHINE GOLD COMPLEXES FOR TREATING BACTERIAL INFECTIONS | AUSPHERIX LIMITED (GB) | 2017-06-08 | — | — | WO | disclosed |