Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | DTYMK | P23919 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422301 | 0.85 | USP2 (0.47) | DDB1CRBNUSP2SMN1; SMN2NR1H2 | |
| SCHEMBL15200845 | 0.83 | USP2 (0.41) | DDB1CRBNUSP2SMN1; SMN2CHRM2 | |
| SCHEMBL28933672 | 0.80 | CHRM2 (0.36) | DDB1CRBNUSP2SMN1; SMN2CHRM2 | |
| SCHEMBL8431612 | 0.79 | SMN1; SMN2 (0.55) | DDB1CRBNDTYMKUSP2SMN1; SMN2 | |
| SCHEMBL31218507 | 0.78 | CHRM2 (0.44) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL17405125 | 0.76 | MEN1 (0.47) | USP2SMN1; SMN2NR1H2MEN1KMT2A | |
| SCHEMBL4796997 | 0.76 | CHRM2 (0.43) | USP2SMN1; SMN2CHRM2CHRM1CHRM3 | |
| SCHEMBL13793654 | 0.74 | MEN1 (0.49) | CRBNBLMMEN1KMT2AKDM4E | |
| SCHEMBL17934203 | 0.74 | MEN1 (0.51) | DDB1CRBNDTYMKUSP2SMN1; SMN2 | |
| SCHEMBL3635546 | 0.74 | P2RX7 (0.45) | DDB1CRBNDTYMKUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3036236-B1 | NOVEL NEUROKININ 1 RECEPTOR ANTAGONIST COMPOUNDS II | LEO PHARMA AS (DK) | 2017-06-07 | — | — | EP | disclosed |