Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15150028 | 1.00 | FFAR1 (0.47) | FFAR1HDAC4CYP4F2CYP4A11CYP3A4 | |
| SCHEMBL3882027 | 1.00 | FFAR1 (0.47) | FFAR1HDAC4CYP4F2CYP4A11CYP3A4 | |
| Hydrochloric Acid SCHEMBL527971 | 0.98 | FFAR1 (0.46) | FFAR1HDAC4CYP4F2CYP4A11CYP3A4 | |
| Hydrochloric Acid SCHEMBL527972 | 0.98 | FFAR1 (0.46) | FFAR1HDAC4CYP4F2CYP4A11CYP3A4 | |
| SCHEMBL18923908 | 0.85 | FAAH (0.40) | HDAC4CYP3A4NAMPTGRM1HRH3 | |
| SCHEMBL3881829 | 0.81 | IDO1 (0.40) | — | |
| SCHEMBL23994457 | 0.81 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL30181805 | 0.81 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL25004996 | 0.81 | FFAR1 (0.55) | FFAR1 | |
| SCHEMBL18541309 | 0.80 | CYP3A4 (0.55) | FFAR1CYP4F2CYP4A11CYP3A4NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676701-B2 | Cyclopropylamine derivatives useful as LSD1 inhibitors | ORYZON GENOMICS, S.A. (ES) | 2017-06-13 | — | — | US | disclosed |
| US-9676701-B2 | Cyclopropylamine derivatives useful as LSD1 inhibitors | ORYZON GENOMICS, S.A. (ES) | 2017-06-13 | — | — | US | disclosed |