Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 2/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16092706 | 0.79 | PTGER4 (0.35) | PTGER4PTGER2 | |
| SCHEMBL18948465 | 0.75 | PTGER4 (0.34) | PTGER4PTGER2 | |
| SCHEMBL18832640 | 0.71 | — | — | |
| SCHEMBL18832507 | 0.71 | — | — | |
| SCHEMBL22025479 | 0.69 | PTGER4 (0.31) | PTGER4PTGER2 | |
| SCHEMBL18827395 | 0.62 | — | — | |
| SCHEMBL23211224 | 0.62 | ACE (0.44) | — | |
| SCHEMBL18832362 | 0.62 | ACE (0.44) | — | |
| SCHEMBL18832608 | 0.60 | — | — | |
| SCHEMBL18832370 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676712-B2 | Lactam compounds as EP4 receptor-selective agonists for use in the treatment of EP4-mediated diseases and conditions | CAYMAN CHEMICAL COMPANY, INC. (US) | 2017-06-13 | — | — | US | disclosed |