Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 1/20 | 0.31 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.31 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18133252 | 0.81 | PTGER4 (0.35) | PTGER4PTGER3PTGER2 | |
| SCHEMBL18943211 | 0.74 | NOTUM (0.30) | — | |
| SCHEMBL18943066 | 0.70 | — | — | |
| SCHEMBL18948464 | 0.69 | PTGER4 (0.31) | PTGER4PTGER2 | |
| SCHEMBL22024924 | 0.64 | NOTUM (0.33) | — | |
| SCHEMBL22025629 | 0.63 | NOTUM (0.32) | — | |
| SCHEMBL18943079 | 0.62 | APLNR (0.31) | — | |
| SCHEMBL16408740 | 0.58 | PTGER4 (0.41) | PTGER4PTGER3PTGER2 | |
| SCHEMBL17808005 | 0.54 | PTGER4 (0.38) | PTGER4PTGER3PTGER2 | |
| SCHEMBL19588832 | 0.52 | P2RX7 (0.42) | PTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3176162-B1 | DIFLUOROLACTAM COMPOUNDS AS EP4 RECEPTOR-SELECTIVE AGONISTS FOR USE IN THE TREATMENT OF EP4-MEDIATED DISEASE AND CONDITIONS | CAYMAN CHEMICAL CO INC (US) | 2020-05-27 | — | — | EP | disclosed |