SCHEMBL18948601

SCHEMBL18948601

CC(P)Oc1ccc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 3/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
ATM Q13315 1/20 0.37
APEX1 P27695 1/20 0.36
ALDH1A1 P00352 4/20 0.34
HPGD P15428 2/20 0.34
ALOX15 P16050 2/20 0.34
HSD17B10 Q99714 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
CYP2C19 P33261 2/20 0.33
MAPT P10636 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
NPC1 O15118 1/20 0.33
PLA2G1B P04054 1/20 0.33
NFKB1 P19838 1/20 0.33
CASP3 P42574 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13019327 0.85 CA1 (0.40) L3MBTL1KDM4ECA1CA2CA9
SCHEMBL27338014 0.83 CA1 (0.41) L3MBTL1KDM4ECA1CA2CA9
SCHEMBL15122416 0.82 APEX1 (0.39) L3MBTL1KDM4ECA1CA2CA9
SCHEMBL19393787 0.81 KDM4E (0.39) L3MBTL1KDM4ECA1CA2CA9
SCHEMBL29445880 0.77 CA1 (0.42) KDM4ECA1CA2CA9ATM
SCHEMBL84279 0.77 CA1 (0.42) KDM4ECA1CA2CA9ATM
SCHEMBL8837901 0.77 TSHR (0.48) CA1CA2CA9APEX1TDP1
SCHEMBL8823303 0.77 TSHR (0.48) CA1CA2CA9APEX1TDP1
SCHEMBL30020052 0.77 TSHR (0.48) CA1CA2CA9APEX1TDP1
SCHEMBL19651157 0.77 L3MBTL1 (0.35) L3MBTL1KDM4ECA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676956-B2 (Meth)acrylic resin composition, film, polarizing plate protective film, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2017-06-13 US disclosed