Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18947643 | 0.96 | S1PR1 (0.48) | S1PR1S1PR3ARNOTUMPLK1 | |
| SCHEMBL18948621 | 0.92 | S1PR1 (0.50) | S1PR1S1PR3ARNOTUMPLK1 | |
| SCHEMBL18371853 | 0.92 | S1PR1 (0.45) | S1PR1S1PR3ARNOTUMPLK1 | |
| SCHEMBL18948618 | 0.90 | S1PR1 (0.56) | S1PR1S1PR3ARNOTUMKIF11 | |
| SCHEMBL18947649 | 0.88 | S1PR1 (0.47) | S1PR1S1PR3ARNOTUMPLK1 | |
| SCHEMBL4636314 | 0.88 | S1PR1 (0.60) | S1PR1S1PR3ARNOTUMKIF11 | |
| SCHEMBL18947647 | 0.86 | S1PR1 (0.52) | S1PR1ARNOTUMMAPTKIF11 | |
| SCHEMBL18371851 | 0.85 | S1PR1 (0.44) | S1PR1S1PR3ARNOTUMMAPT | |
| SCHEMBL18948603 | 0.84 | S1PR1 (0.51) | S1PR1ARNOTUMKIF11TAS2R14 | |
| SCHEMBL18371852 | 0.84 | PTGS2 (0.41) | S1PR1S1PR3ARPLK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676906-B1 | Polymer of poly(arylene ether)s, manufacturing method thereof and polymer light emitting diode with organic light emitting layer made from the same | NATIONAL SUN YAT-SEN UNIVERSITY (TW) | 2017-06-13 | — | — | US | disclosed |