Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12599115 | 0.82 | CHRNA7 (0.35) | CHRNA7LMNACHRM2ADRA2ACYP2D6 | |
| SCHEMBL888618 | 0.81 | CHRNA7 (0.34) | CHRNA7LMNACHRM2ADRA2ACYP2D6 | |
| SCHEMBL19364843 | 0.77 | — | — | |
| SCHEMBL21897249 | 0.72 | — | — | |
| SCHEMBL890062 | 0.71 | LMNA (0.38) | CHRNA7LMNACHRM2ADRA2ACYP2D6 | |
| SCHEMBL24754130 | 0.69 | — | — | |
| SCHEMBL18671430 | 0.69 | — | — | |
| SCHEMBL10216998 | 0.68 | LMNA (0.34) | CHRNA7LMNACHRM2ADRA2ACYP2D6 | |
| SCHEMBL10147273 | 0.68 | CHRNA7 (0.41) | CHRNA7LMNACHRM2ADRA2ACYP2D6 | |
| SCHEMBL29341677 | 0.67 | CYP2D6 (0.46) | CHRNA7LMNACHRM2ADRA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |