Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA4 | P22748 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL753972 | 0.85 | MAPT (0.51) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL890090 | 0.85 | MAPT (0.51) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL888846 | 0.82 | MAPT (0.49) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL8908249 | 0.81 | ALDH1A1 (0.50) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL8915578 | 0.81 | MAPT (0.47) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL10077257 | 0.77 | MAPT (0.44) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL4908474 | 0.73 | MAPT (0.58) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL5372649 | 0.73 | MAPT (0.58) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL5114155 | 0.71 | ALDH1A1 (0.55) | MAPTMAPK1TDP1CYP1A2CYP3A4 | |
| SCHEMBL529767 | 0.71 | TSHR (0.51) | MAPTMAPK1TDP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |