Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 4/20 | 0.33 |
| ▸ | BCHE | P06276 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19734035 | 0.78 | LMNA (0.48) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL22676127 | 0.77 | LMNA (0.44) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL24757633 | 0.76 | LMNA (0.47) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL30322428 | 0.73 | LMNA (0.52) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL7122025 | 0.73 | LMNA (0.52) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL27304478 | 0.72 | LMNA (0.43) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL24296580 | 0.71 | PTGS1 (0.48) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL19890521 | 0.70 | LMNA (0.44) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL1302119 | 0.70 | TYR (0.58) | PTGS1TRPA1CACNA1CLMNATYR | |
| SCHEMBL7804625 | 0.70 | LMNA (0.52) | PTGS1TRPA1CACNA1CLMNATYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676802-B2 | Hepatitis C virus inhibitors | ENANTA PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |