Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19682255 | 0.91 | ADRA2A (0.39) | ADRA2AADRA2BADRA2C | |
| SCHEMBL22353466 | 0.87 | CNR1 (0.34) | ADRA2AADRA2BADRA2C | |
| SCHEMBL22353570 | 0.85 | ADRA2A (0.37) | ADRA2AADRA2BADRA2C | |
| SCHEMBL18949127 | 0.82 | CNR1 (0.34) | ADRA2AADRA2BADRA2C | |
| SCHEMBL19682136 | 0.82 | CNR1 (0.34) | ADRA2AADRA2BADRA2C | |
| SCHEMBL18949087 | 0.82 | ADRA2A (0.39) | ADRA2AADRA2BADRA2C | |
| SCHEMBL18949084 | 0.82 | ADRA2A (0.39) | ADRA2AADRA2BADRA2C | |
| SCHEMBL18949167 | 0.78 | ADRA2A (0.42) | ADRA2AADRA2BADRA2C | |
| SCHEMBL18949157 | 0.78 | ADRA2A (0.42) | ADRA2AADRA2BADRA2C | |
| SCHEMBL18949217 | 0.78 | ADRA2A (0.42) | ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676748-B2 | Compounds and methods for kinase modulation, and indications therefor | PLEXXIKON INC. (US) | 2017-06-13 | — | — | US | disclosed |