Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 15/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 15/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 15/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16193204 | 0.94 | TSHR (0.47) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL22667518 | 0.88 | TSHR (0.49) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL2531577 | 0.87 | TSHR (0.56) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL12018013 | 0.86 | SCN1A (0.48) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL19316669 | 0.85 | TSHR (0.40) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL19316647 | 0.83 | TSHR (0.39) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL19316649 | 0.83 | TSHR (0.39) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL22058363 | 0.83 | TSHR (0.45) | TSHRALDH1A1TP53NPC1HTT | |
| SCHEMBL9812643 | 0.82 | TSHR (0.46) | TSHRALDH1A1ADRB2ADRB1ADRB3 | |
| SCHEMBL10963020 | 0.82 | ALDH1A1 (0.50) | TSHRALDH1A1ADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9675529-B2 | Dental composition containing high refractive index monomers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2017-06-13 | — | — | US | disclosed |