Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | TSHR | P16473 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | USP2 | O75604 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 3/20 | 0.61 |
| ▸ | APAF1 | O14727 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | MAPT | P10636 | 3/20 | 0.61 |
| ▸ | RAD52 | P43351 | 3/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.61 |
| ▸ | UBE2N | P61088 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 9/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL15439706 | 0.86 | LMNA (0.60) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| SCHEMBL11127399 | 0.86 | LMNA (0.59) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| SCHEMBL11129443 | 0.84 | LMNA (0.56) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| SCHEMBL18407118 | 0.79 | LMNA (0.67) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| SCHEMBL10037912 | 0.79 | SMN1; SMN2 (0.64) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| SCHEMBL13058931 | 0.79 | LMNA (0.55) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| Methylbenzethonium SCHEMBL790480 | 0.77 | LMNA (1.00) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| Methylbenzethonium SCHEMBL29630503 | 0.77 | LMNA (1.00) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| Methylbenzethonium SCHEMBL7065208 | 0.76 | LMNA (0.98) | LMNATSHRTDP1CYP2D6CYP1A2 | |
| Methylbenzethonium SCHEMBL136062 | 0.76 | SMN1; SMN2 (1.00) | LMNATSHRTDP1CYP2D6CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9675623-B2 | Non-surgical method of treatment for cataract | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-06-13 | — | — | US | disclosed |