Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.36 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2083264 | 0.88 | MEN1 (0.40) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL29980565 | 0.86 | MEN1 (0.39) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL29457319 | 0.86 | MEN1 (0.39) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL2083261 | 0.86 | MEN1 (0.39) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL2083262 | 0.86 | MEN1 (0.39) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL2086908 | 0.85 | MEN1 (0.38) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL2086904 | 0.85 | MEN1 (0.38) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL9145758 | 0.80 | NPSR1 (0.40) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL9145755 | 0.80 | NPSR1 (0.40) | MEN1KMT2ANPSR1MAPTLMNA | |
| SCHEMBL2524465 | 0.78 | MEN1 (0.35) | MEN1KMT2ANPSR1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676774-B2 | Compounds and compositions for treatment of cancer | SUNESIS PHARMACEUTICALS, INC. (US) | 2017-06-13 | — | — | US | disclosed |