Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | DHODH | Q02127 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPY1R | P25929 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9145758 | 1.00 | NPSR1 (0.40) | NPSR1MEN1KMT2ASLC6A12MAPT | |
| SCHEMBL2082830 | 0.86 | NPSR1 (0.38) | NPSR1MEN1KMT2ASLC6A12MAPT | |
| SCHEMBL2082832 | 0.86 | NPSR1 (0.38) | NPSR1MEN1KMT2ASLC6A12MAPT | |
| SCHEMBL7956810 | 0.83 | CYP2C19 (0.49) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL7956814 | 0.83 | CYP2C19 (0.49) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5256943 | 0.82 | KEAP1 (0.40) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL5256945 | 0.82 | KEAP1 (0.40) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL10551035 | 0.82 | KEAP1 (0.40) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL18949530 | 0.80 | MEN1 (0.41) | NPSR1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL10375594 | 0.80 | USP2 (0.46) | NPSR1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |