Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 20/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL161856 | 0.89 | NAMPT (0.73) | NAMPT | |
| SCHEMBL18949586 | 0.87 | NAMPT (0.65) | NAMPT | |
| SCHEMBL18949604 | 0.85 | NAMPT (0.67) | NAMPT | |
| SCHEMBL18949511 | 0.84 | NAMPT (0.65) | NAMPT | |
| SCHEMBL18949579 | 0.81 | NAMPT (0.63) | NAMPT | |
| SCHEMBL18949572 | 0.81 | NAMPT (0.63) | NAMPT | |
| SCHEMBL18949557 | 0.80 | NAMPT (0.66) | NAMPT | |
| SCHEMBL18949580 | 0.78 | NAMPT (0.65) | NAMPT | |
| SCHEMBL18949594 | 0.78 | NAMPT (0.62) | NAMPT | |
| SCHEMBL160777 | 0.78 | NAMPT (0.70) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9676721-B2 | Compounds and compositions for the inhibition of NAMPT | FORMA TM, LLC (US) | 2017-06-13 | — | — | US | disclosed |