SCHEMBL18949688

SCHEMBL18949688

C=CC(=O)Oc1ccc(COc2ccc(C(C)=O)cc2)cc1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOB P27338 11/20 0.66
MAOA P21397 2/20 0.64
ALDH1A1 P00352 1/20 0.61
HTT P42858 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61
HRH3 Q9Y5N1 5/20 0.57
THRB P10828 2/20 0.55
PARP10 Q53GL7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26362166 0.89 THRB (0.62) MAOBMAOASMN1; SMN2THRBPARP10
SCHEMBL898885 0.86 MAPT (0.57) MAOBSMN1; SMN2L3MBTL1THRB
SCHEMBL18904698 0.85 PARP10 (0.73) MAOBALDH1A1THRBPARP10
SCHEMBL26362245 0.84 THRB (0.57) MAOBSMN1; SMN2THRBPARP10
SCHEMBL22566459 0.84 THRB (0.57) MAOBSMN1; SMN2THRBPARP10
SCHEMBL22566611 0.84 THRB (0.57) MAOBSMN1; SMN2THRBPARP10
SCHEMBL26362173 0.84 THRB (0.54) MAOBMAOAALDH1A1HTTSMN1; SMN2
SCHEMBL26362171 0.84 THRB (0.54) MAOBMAOAALDH1A1HTTSMN1; SMN2
SCHEMBL28707031 0.84 MAOB (0.68) MAOBMAOAALDH1A1HTTSMN1; SMN2
SCHEMBL24844714 0.83 FFAR1 (0.55) MAOBALDH1A1THRBPARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180037817-A1 POLYMERIZABLE COMPOSITION AND OPTICALLY ANISOTROPIC BODY DIC CORPORATION (JP) 2018-02-08 US disclosed
US-9676959-B2 Polymerizable composition solution and optically anisotropic body including the same DIC CORPORATION (JP) 2017-06-13 US disclosed