Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 3/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25918883 | 0.89 | DRD2 (0.45) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL13202379 | 0.84 | DRD2 (0.47) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL912304 | 0.84 | DRD2 (0.47) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL912303 | 0.84 | DRD2 (0.47) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL227250 | 0.81 | DRD2 (0.45) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL227251 | 0.81 | DRD2 (0.45) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL1543495 | 0.80 | BTK (0.51) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL30942791 | 0.80 | DRD2 (0.48) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL622419 | 0.80 | BTK (0.51) | DRD2BTKKDM1AMAOBEPHX1 | |
| SCHEMBL28480020 | 0.80 | DRD2 (0.48) | DRD2BTKKDM1AMAOBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3057942-B1 | 1,4-CYCLOHEXYLAMINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | CHEMO RES S L (ES) | 2017-06-14 | — | — | EP | disclosed |