SCHEMBL1895086

SCHEMBL1895086

C[C@@H]1C[C@H](N(C=O)Cc2cc(C(F)(F)F)cc(C(F)(F)F)c2)c2cc(C(F)(F)F)ccc2N1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CETP P11597 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1565594 0.89 CETP (0.62) CETP
SCHEMBL993197 0.89 CETP (0.62) CETP
SCHEMBL993410 0.87 CETP (0.69) CETP
SCHEMBL6461793 0.87 CETP (0.69) CETP
SCHEMBL7044859 0.83 CETP (0.70) CETP
SCHEMBL6589157 0.81 CETP (0.51) CETP
SCHEMBL992971 0.81 CETP (0.77) CETP
SCHEMBL5955669 0.81 CETP (0.77) CETP
SCHEMBL6588147 0.81 CETP (0.55) CETP
SCHEMBL4963327 0.79 CETP (0.60) CETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2319509-A1 Method of Inhibiting remnant lipoprotein production Japan Tobacco, Inc. (JP) 2011-05-11 EP disclosed
EP-2316447-A1 Method of inhibiting remnant lipoprotein production Japan Tobacco, Inc. (JP) 2011-05-04 EP disclosed