Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 20/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6587826 | 0.91 | CETP (0.59) | CETP | |
| SCHEMBL6588658 | 0.89 | CETP (0.49) | CETP | |
| SCHEMBL6588147 | 0.89 | CETP (0.55) | CETP | |
| SCHEMBL1565594 | 0.89 | CETP (0.62) | CETP | |
| SCHEMBL993197 | 0.89 | CETP (0.62) | CETP | |
| SCHEMBL6591162 | 0.87 | CETP (0.68) | CETP | |
| SCHEMBL6588300 | 0.86 | CETP (0.69) | CETP | |
| SCHEMBL6592421 | 0.83 | CETP (0.46) | CETP | |
| SCHEMBL1895086 | 0.81 | CETP (0.53) | CETP | |
| SCHEMBL992971 | 0.81 | CETP (0.77) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1114032-B1 | 4-AMINO SUBSTITUTED-2-SUBSTITUTED-1,2,3,4-TETRAHYDROQUINOLINES AS CETP INHIBITORS | PFIZER PROD INC (US) | 2004-06-02 | — | — | EP | claimed |