Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18790800 | 0.85 | TAS2R38 (0.33) | CRBNTAS2R38 | |
| SCHEMBL21757071 | 0.84 | — | — | |
| SCHEMBL21654998 | 0.84 | — | — | |
| SCHEMBL18658467 | 0.84 | — | — | |
| SCHEMBL29314108 | 0.83 | — | — | |
| SCHEMBL14463060 | 0.81 | TSHR (0.35) | ALDH1A1 | |
| SCHEMBL18404292 | 0.80 | CNR2 (0.33) | CRBNTAS2R38 | |
| SCHEMBL21654989 | 0.79 | — | — | |
| SCHEMBL26054042 | 0.79 | — | — | |
| SCHEMBL23982848 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2981536-B1 | N-PHENYL-CARBOXAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UC (IE) | 2017-06-14 | — | — | EP | disclosed |