Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27835475 | 0.78 | ALDH1A1 (0.37) | ALDH1A1GAAPOLBKDM4E | |
| SCHEMBL22359083 | 0.77 | — | — | |
| SCHEMBL10522126 | 0.74 | ALDH1A1 (0.43) | ALDH1A1GAAPOLBMAPTKDM4E | |
| SCHEMBL21254235 | 0.71 | ALDH1A1 (0.35) | ALDH1A1GAAPOLB | |
| SCHEMBL899170 | 0.70 | — | — | |
| SCHEMBL18951895 | 0.69 | — | — | |
| SCHEMBL15580363 | 0.68 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL16607603 | 0.67 | ALDH1A1 (0.35) | ALDH1A1GAAPOLB | |
| SCHEMBL21092294 | 0.67 | ALDH1A1 (0.35) | ALDH1A1GAAPOLB | |
| SCHEMBL23505917 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002283-B1 | THIAZOLE DERIVATIVES | KYOWA HAKKO KIRIN CO LTD (JP) | 2017-06-14 | — | — | EP | disclosed |