Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 20/20 | 1.00 |
| ▸ | MAOA | P21397 | 19/20 | 1.00 |
| ▸ | MAOB | P27338 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15541008 | 1.00 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL15541007 | 1.00 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL15541945 | 1.00 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL4129786 | 1.00 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL15767313 | 1.00 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| SCHEMBL23465403 | 1.00 | KDM1A (1.00) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL17223474 | 0.98 | MAOA (1.00) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL17223470 | 0.98 | MAOA (1.00) | KDM1AMAOAMAOB | |
| Hydrochloric Acid SCHEMBL17223469 | 0.98 | MAOA (1.00) | KDM1AMAOAMAOB | |
| Trifluoroacetic Acid SCHEMBL17223483 | 0.84 | KDM1A (0.70) | KDM1AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097865-A9 | COMBINATION OF CALORIC RESTRICTION (CR) OR IGF1/INSULIN RECEPTOR INHIBITOR WITH LSD1 INHIBITOR | ISTITUTO EUROPEO DI ONCOLOGIA (IT) | 2017-08-31 | — | — | WO | disclosed |
| WO-2017097865-A1 | COMBINATION OF CALORIC RESTRICTION (CR) OR IGF1/INSULIN RECEPTOR INHIBITOR WITH LSD1 INHIBITOR | ISTITUTO EUROPEO DI ONCOLOGIA (IT) | 2017-06-15 | — | — | WO | disclosed |