⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6299008 | 0.98 | LMNA (0.48) | — | |
| SCHEMBL2238495 | 0.83 | LMNA (0.48) | — | |
| SCHEMBL30643951 | 0.81 | — | — | |
| SCHEMBL11860376 | 0.80 | LMNA (0.47) | — | |
| SCHEMBL2056168 | 0.77 | — | — | |
| SCHEMBL96071 | 0.75 | — | — | |
| SCHEMBL5808175 | 0.75 | — | — | |
| SCHEMBL5808177 | 0.75 | — | — | |
| SCHEMBL314480 | 0.75 | — | — | |
| SCHEMBL3906075 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 875 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117003705-A | Novel 1,2, 3-triazole compound with anti-tumor effect, and preparation method and application thereof | 北京中医药大学 | 2023-11-07 | — | — | CN | claimed |
| CN-116284046-A | Ballon Sha Wei derivative, and preparation method and application thereof | 山东新华制药股份有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-112979571-A | AKR1C3 selective inhibitor, preparation method and application thereof | 中国药科大学 | 2021-06-18 | — | — | CN | claimed |
| US-20180273906-A1 | MICROVESICLE AND STEM CELL COMPOSITIONS FOR THERAPEUTIC APPLICATIONS | IPS HEART | 2018-09-27 | — | — | US | claimed |
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| CN-122059992-A | AKR1C3 selectively activated small molecule drug conjugate and application thereof | 中国药科大学 | 2026-05-19 | — | — | CN | disclosed |
| CN-122036638-A | AKR1C3 inhibitor with tricyclic structure and application thereof | 中国药科大学 | 2026-05-15 | — | — | CN | disclosed |
| US-12486258-B2 | Compounds and methods for regulating insulin secretion | THE BROAD INSTITUTE, INC. (US) | 2025-12-02 | — | — | US | disclosed |
| CN-119591637-A | Compound with aryl amide structure and medical application thereof | 南京芩领医药科技有限公司 | 2025-03-11 | — | — | CN | disclosed |
| CN-118994135-A | Compound with aryl amide structure and medical application thereof | 南京芩领医药科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-118994241-A | Compound with aryl amide structure and application thereof | 南京芩领医药科技有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20240368133-A1 | Compounds for the Treatment of Pain, in Particular, Neuropathic Pain, and/or Other Diseases or Disorders that are Associated with AT2R and/or AT2R Mediated Signaling | CONFO THERAPEUTICS N.V. (BE) | 2024-11-07 | — | — | US | disclosed |
| US-4024271-A | INHIBITORS OF HISTAMINE ACTIVITY | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-17 | — | — | US | disclosed |
| US-4022797-A | PHARMACEUTICALS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-05-10 | — | — | US | disclosed |
| US-4018931-A | INHIBITION OF H-2 HISTAMINE RECEPTORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1977-04-19 | — | — | US | disclosed |
| US-3985771-A | Total steroid synthesis employing substituted isoxazole derivatives | HOFFMANN-LA ROCHE INC. (US) | 1976-10-12 | — | — | US | disclosed |
| US-3984428-A | Isoxazolyl-substituted perhydrobenzindenes | HOFFMANN-LA ROCHE INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3984427-A | Preparation of vinyl lactones and corresponding Mannich bases | HOFFMANN-LA ROCHE INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3950333-A | HISTAMINE INHIBITORS, OXYALKYL, THIOALKYL, AMINOALKYL DERIVATIVES | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |
| US-3950353-A | HISTAMINE INHIBITORS | SMITH KLINE & FRENCH LABORATORIES LIMITED (EN) | 1976-04-13 | — | — | US | disclosed |