Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | CTSC | P53634 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 7/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18953253 | 1.00 | HPGD (0.42) | HPGDCD274GRM5CTSCSLC6A2 | |
| SCHEMBL18953247 | 0.85 | HPGD (0.42) | HPGDCD274GRM5CTSCALDH1A1 | |
| SCHEMBL18953248 | 0.85 | HPGD (0.42) | HPGDCD274GRM5CTSCALDH1A1 | |
| SCHEMBL29902300 | 0.84 | HPGD (0.53) | HPGDGRM5SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18591276 | 0.84 | HPGD (0.53) | HPGDGRM5SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL18555022 | 0.83 | HPGD (0.51) | HPGDGRM5SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL29545627 | 0.83 | HPGD (0.51) | HPGDGRM5SLC6A2SLC6A4SLC6A3 | |
| Hydrochloric Acid SCHEMBL18555021 | 0.83 | HPGD (0.51) | HPGDGRM5SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18953213 | 0.82 | HPGD (0.40) | HPGDCD274GRM5CDK5CFD | |
| SCHEMBL18953214 | 0.82 | HPGD (0.40) | HPGDCD274GRM5CDK5CFD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190127366-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | ATTUNE PHARMACEUTICALS, INC. | 2019-05-02 | — | — | US | disclosed |
| EP-3386504-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | Lifesci Pharmaceuticals, Inc. (BB) | 2018-10-17 | — | — | EP | disclosed |
| WO-2017098328-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHAMACEUTICALS, INC. (BB) | 2017-06-15 | — | — | WO | disclosed |
| WO-2017098328-A2 | THERAPEUTIC INHIBITORY COMPOUNDS | LIFESCI PHAMACEUTICALS, INC. (BB) | 2017-06-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190127366-A1 | THERAPEUTIC INHIBITORY COMPOUNDS | CFD, CFH, C9 | HPGD 647/4885CD274 827/4885GRM5 2416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.