Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.41 |
| ▸ | SQLE | Q14534 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | FNTA | P49354 | 1/20 | 0.34 |
| ▸ | FNTB | P49356 | 1/20 | 0.34 |
| ▸ | ICMT | O60725 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18955353 | 1.00 | KMT2A (0.46) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL18955323 | 0.98 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL18955325 | 0.98 | KMT2A (0.50) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL2522877 | 0.86 | KMT2A (0.38) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL4451127 | 0.83 | KMT2A (0.42) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL4451128 | 0.83 | KMT2A (0.42) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8700830 | 0.81 | KMT2A (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10509053 | 0.81 | KMT2A (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8700827 | 0.81 | KMT2A (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL10509048 | 0.81 | KMT2A (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100514-A1 | LIPOPHILIC ANALOGS OF CJ-16264, METHODS OF USE, AND SYNTHESIS THEREOF | WILLIAM MARSH RICE UNIVERSITY (US) | 2017-06-15 | — | — | WO | claimed |
| WO-2017100514-A1 | LIPOPHILIC ANALOGS OF CJ-16264, METHODS OF USE, AND SYNTHESIS THEREOF | WILLIAM MARSH RICE UNIVERSITY (US) | 2017-06-15 | — | — | WO | disclosed |