SCHEMBL8700827

SCHEMBL8700827

[CH]=C(C)CC/C=C(\C)CCC=C(C)C

nearest known ligand 0.73

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.73
MAPT P10636 2/20 0.64
MEN1 O00255 2/20 0.64
CYP3A4 P08684 2/20 0.64
ALOX15 P16050 2/20 0.64
ALDH1A1 P00352 1/20 0.64
UGT1A1 P22309 1/20 0.64
SQLE Q14534 7/20 0.61
KDM4E B2RXH2 1/20 0.57
FNTA P49354 1/20 0.52
FNTB P49356 1/20 0.52
ICMT O60725 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8700830 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL10509048 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL10509053 1.00 KMT2A (0.73) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL9492196 0.90
SCHEMBL2771003 0.90
SCHEMBL23802597 0.85 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Squalene SCHEMBL890053 0.85 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL21639794 0.85 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
SCHEMBL8013144 0.85 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15
Squalene SCHEMBL8819997 0.85 KMT2A (1.00) KMT2AMAPTMEN1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115197078-B Pegylated lipid and modified liposome thereof, pharmaceutical composition containing liposome and preparation and application of pharmaceutical composition 厦门赛诺邦格生物科技股份有限公司 2024-06-04 CN claimed
EP-4321504-A1 PEGYLATED LIPID AND LIPOSOME MODIFIED THEREBY, AND PHARMACEUTICAL COMPOSITION COMPRISING LIPOSOME AND PREPARATION AND USE THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2024-02-14 EP claimed
CN-117510830-A Pegylated lipid and modified liposome thereof, pharmaceutical composition containing liposome and preparation and application of pharmaceutical composition 厦门赛诺邦格生物科技股份有限公司 2024-02-06 CN claimed
CN-117327270-A Pegylated lipid and modified liposome thereof, pharmaceutical composition containing liposome and preparation and application of pharmaceutical composition 厦门赛诺邦格生物科技股份有限公司 2024-01-02 CN claimed
CN-117304473-A Pegylated lipid and modified liposome thereof, pharmaceutical composition containing liposome and preparation and application of pharmaceutical composition 厦门赛诺邦格生物科技股份有限公司 2023-12-29 CN claimed
EP-4276090-A1 CATIONIC LIPID, LIPOSOME CONTAINING CATIONIC LIPID, AND NUCLEIC-ACID PHARMACEUTICAL COMPOSITION CONTAINING LIPOSOME AND PREPARATION AND APPLICATION THEREOF Xiamen Sinopeg Biotech Co., Ltd. (CN) 2023-11-15 EP claimed
EP-2816053-B1 BASE-PROTECTED OLIGONUCLEOTIDE AJINOMOTO KK (JP) 2021-03-24 EP claimed
US-20210009495-A1 METHOD FOR THE ISOMERIZATION OF A 3-(Z)-UNSATURATED CARBOXYLIC ACID TO THE 3-(E)-ISOMER BASF SE (DE) 2021-01-14 US claimed
EP-3752478-A1 METHOD FOR THE ISOMERIZATION OF A 3-(Z)-UNSATURATED CARBOXYLIC ACID TO THE 3-(E)-ISOMER BASF SE (DE) 2020-12-23 EP claimed
CN-111741943-A Process for isomerizing 3- (Z) -unsaturated carboxylic acids to 3- (E) -isomers 巴斯夫欧洲公司 2020-10-02 CN claimed
EP-2816053-A1 BASE-PROTECTED OLIGONUCLEOTIDE Ajinomoto Co., Inc. (JP) 2014-12-24 EP claimed
EP-2792368-A1 LIPID NANOPARTICLES CONTAINING COMBINATIONS OF CATIONIC LIPIDS Kyowa Hakko Kirin Co., Ltd. (JP) 2014-10-22 EP claimed
US-8846885-B2 Oligonucleotide with protected base AJINOMOTO CO., INC. (JP) 2014-09-30 US claimed
EP-2774912-A1 CATIONIC LIPID Kyowa Hakko Kirin Co., Ltd. (JP) 2014-09-10 EP claimed
US-20140044755-A1 RNAi PHARMACEUTICAL COMPOSITION FOR SUPPRESSING EXPRESSION OF KRAS GENE KYOWA HAKKO KIRIN CO., LTD. (JP) 2014-02-13 US claimed
US-20140045913-A1 LIPID NANO PARTICLES COMPRISING COMBINATION OF CATIONIC LIPID KYOWA HAKKO KIRIN CO., LTD. (JP) 2014-02-13 US claimed
US-20130280305-A1 CATIONIC LIPID KYOWA HAKKO KIRIN CO., LTD. (JP) 2013-10-24 US claimed
US-20130267697-A1 OLIGONUCLEOTIDE WITH PROTECTED BASE AJINOMOTO CO., INC. (JP) 2013-10-10 US claimed
US-20130108685-A1 CATIONIC LIPID KYOWA KIRIN CO., LTD. (JP) 2013-05-02 US claimed
EP-2567951-A1 CATIONIC LIPID Kyowa Hakko Kirin Co., Ltd. (JP) 2013-03-13 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140045913-A1 LIPID NANO PARTICLES COMPRISING COMBINATION OF CATIONIC LIPID LPAR3, APOL1, PLIN3 KMT2A 3110/4885MAPT 4116/4885MEN1 2209/4885
US-20130108685-A1 CATIONIC LIPID LPAR3, ACOX3, H1-3 KMT2A 2504/4885MAPT 4637/4885MEN1 2079/4885
US-20130280305-A1 CATIONIC LIPID LPAR3, ACOX3, H1-3 KMT2A 2504/4885MAPT 4637/4885MEN1 2079/4885
US-20210009495-A1 METHOD FOR THE ISOMERIZATION OF A 3-(Z)-UNSATURATED CARBOXYLIC ACID TO THE 3-(E)-ISOMER HCAR2, HCAR1, AKR1C3 KMT2A 2629/4885MAPT 4842/4885MEN1 3160/4885
US-20130267697-A1 OLIGONUCLEOTIDE WITH PROTECTED BASE POLRMT, POLN, RNGTT KMT2A 2562/4885MAPT 2765/4885MEN1 3770/4885
US-20140044755-A1 RNAi PHARMACEUTICAL COMPOSITION FOR SUPPRESSING EXPRESSION OF KRAS GENE KRAS, NRAS, HRAS KMT2A 1416/4885MAPT 4620/4885MEN1 1033/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.