⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899064 | 0.81 | — | — | |
| SCHEMBL4201267 | 0.72 | ADH1B (0.56) | — | |
| SCHEMBL20080360 | 0.72 | ADH1B (0.56) | — | |
| SCHEMBL4201273 | 0.72 | ADH1B (0.56) | — | |
| SCHEMBL1892103 | 0.72 | — | — | |
| SCHEMBL12895646 | 0.71 | — | — | |
| SCHEMBL15829904 | 0.69 | — | — | |
| SCHEMBL15744 | 0.69 | — | — | |
| SCHEMBL21280277 | 0.68 | — | — | |
| SCHEMBL22755592 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148030-A1 | KETO ACID BIOPOLYMERS AND POLYOL KETO ESTERS AND USES THEREOF | ATOSSA THERAPEUTICS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024018403-A1 | SUBSTITUTED IMIDAZOAMIDE COMPOUNDS, AND METHODS USING SAME | ARBUTUS BIOPHARMA CORPORATION (CA) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023066292-A1 | TRICYCLIC BORONIC ACID DERIVATIVE, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 上海济煜医药科技有限公司 | 2023-04-27 | — | — | WO | disclosed |
| EP-2668180-B1 | BCL-2/BCL-XL INHIBITORS FOR USE IN THE TREATMENT OF CANCER | UNIV MICHIGAN REGENTS (US) | 2018-08-01 | — | — | EP | disclosed |
| US-10004702-B2 | Linear guanidine derivatives, methods of preparation and uses thereof | LEAD DISCOVERY SIENA S.R.L. (IT) | 2018-06-26 | — | — | US | disclosed |
| WO-2017197488-A1 | LIBRARIES OF DIVERSE MACROCYCLIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME | CYCLENIUM PHARMA INC. (CA) | 2017-11-23 | — | — | WO | disclosed |
| US-20170304235-A1 | LINEAR GUANIDINE DERIVATIVES, METHODS OF PREPARATION AND USES THEREOF | LEAD DISCOVERY SIENA S.R.L. (IT) | 2017-10-26 | — | — | US | disclosed |
| US-20170096692-A1 | CELL-FREE PREPARATION OF CARBAPENEMS | GREENLIGHT BIOSCIENCES, INC. (US) | 2017-04-06 | — | — | US | disclosed |
| US-9469861-B2 | Cell-free preparation of carbapenems | GREENLIGHT BIOSCIENCES, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| WO-2016105448-A1 | IMIDAZOLINE RECEPTOR TYPE 1 LIGANDS FOR USE AS THERAPEUTICS | RIDEOUT DARRYL (US) | 2016-06-30 | — | — | WO | disclosed |
| WO-2006076243-A1 | PROCESSES FOR PREPARING 4-(PHENOXY-5-METHYL-PYRIMIDIN-4-YLOXY)PIPERIDINE-1-CARBOXYLIC ACID DERIVATIVES AND RELATED COMPOUNDS | ARENA PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | WO | disclosed |
| WO-2006076455-A2 | PROCESSES FOR PREPARING PYRAZOLO[3,4-D]PYRIMIDINE ETHERS | ARENA PHARMACEUTICALS, INC. (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060154940-A1 | Processes for preparing pyrazolo[3,4-d]pyrimidine ethers | ARENA PHARMACEUTICALS, INC. | 2006-07-13 | — | — | US | disclosed |
| US-20060155129-A1 | Processes for preparing aromatic ethers | ARENA PHARMACEUTICALS, INC. | 2006-07-13 | — | — | US | disclosed |
| WO-2006069242-A2 | FUSED PYRAZOLE DERIVATIVES AND USES THEREOF IN METHODS OF TREATMENT OF METABOLIC-RELATED?DISORDERS | ARENA PHARMACEUTICALS, INC. (US) | 2006-06-29 | — | — | WO | disclosed |
| WO-2005113553-A2 | AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE | BAYER CROPSCIENCE AG (DE) | 2005-12-01 | — | — | WO | disclosed |
| WO-2005007647-A9 | TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO | ARENA PHARM INC (US) | 2005-04-07 | — | — | WO | disclosed |
| US-20050070562-A1 | Trisubstituted aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto | ARENA PHARMACEUTICALS, INC. | 2005-03-31 | — | — | US | disclosed |
| US-5264448-A | Thioamides, oxazole ring, insecticides, miticides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-11-23 | — | — | US | disclosed |
| EP-0394043-A1 | An amide compound and its production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1990-10-24 | — | — | EP | disclosed |