Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 20/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5182418 | 0.81 | SIGMAR1 (0.94) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL5184453 | 0.79 | SIGMAR1 (0.58) | SIGMAR1KCNH2 | |
| SCHEMBL467012 | 0.78 | SIGMAR1 (1.00) | SIGMAR1KCNH2HTR2B | |
| SCHEMBL467378 | 0.78 | SIGMAR1 (0.71) | SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL1895222 | 0.78 | SIGMAR1 (0.98) | SIGMAR1KCNH2HTR2B | |
| Hydrochloric Acid SCHEMBL1897409 | 0.78 | SIGMAR1 (0.70) | SIGMAR1KCNH2 | |
| SCHEMBL467018 | 0.77 | SIGMAR1 (0.74) | SIGMAR1KCNH2 | |
| SCHEMBL467024 | 0.77 | SIGMAR1 (0.81) | SIGMAR1KCNH2 | |
| SCHEMBL467083 | 0.76 | SIGMAR1 (0.83) | SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL1897470 | 0.75 | SIGMAR1 (0.81) | SIGMAR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2325174-A1 | Sigma receptor inhibitors | Laboratorios Del. Dr. Esteve, S.A. (ES) | 2011-05-25 | — | — | EP | claimed |