Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASGR1 | P07306 | 13/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18960839 | 0.87 | ASGR1 (0.54) | ASGR1 | |
| SCHEMBL18960838 | 0.87 | ASGR1 (0.54) | ASGR1 | |
| SCHEMBL18960831 | 0.82 | ASGR1 (0.49) | ASGR1 | |
| SCHEMBL18960836 | 0.78 | ASGR1 (0.46) | ASGR1 | |
| SCHEMBL18960835 | 0.75 | ASGR1 (0.44) | ASGR1 | |
| SCHEMBL18960833 | 0.75 | ASGR1 (0.44) | ASGR1 | |
| SCHEMBL18960837 | 0.74 | ASGR1 (0.46) | ASGR1 | |
| SCHEMBL18960834 | 0.73 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL18960832 | 0.73 | ASGR1 (0.42) | ASGR1 | |
| SCHEMBL21500353 | 0.71 | ASGR1 (1.00) | ASGR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170165284-A1 | SUBSTITUTED-6,8-DIOXABICYCLO[3.2.1]OCTANE-2,3-DIOL COMPOUNDS AS TARGETING AGENTS OF ASGPR | PFIZER INC. (US) | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170165284-A1 | SUBSTITUTED-6,8-DIOXABICYCLO[3.2.1]OCTANE-2,3-DIOL COMPOUNDS AS TARGETING AGENTS OF ASGPR | ASGR1, MRGPRX2, LDLR | ASGR1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.