Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | POLA1 | P09884 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PAM | P19021 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13886959 | 0.98 | CNR2 (0.47) | CNR2TRPV1POLBPOLA1DGKA | |
| SCHEMBL24977871 | 0.86 | ALDH1A1 (0.40) | CNR2TRPV1POLBPOLA1TSHR | |
| SCHEMBL7157837 | 0.86 | HSP90AA1 (0.55) | CNR2TRPV1POLBPOLA1DGKA | |
| SCHEMBL9305133 | 0.86 | HSP90AA1 (0.55) | CNR2TRPV1POLBPOLA1DGKA | |
| SCHEMBL30186702 | 0.86 | HSP90AA1 (0.55) | CNR2TRPV1POLBPOLA1DGKA | |
| SCHEMBL8423003 | 0.86 | HSP90AA1 (0.55) | CNR2TRPV1POLBPOLA1DGKA | |
| SCHEMBL8590568 | 0.86 | HSP90AA1 (0.55) | CNR2TRPV1POLBPOLA1DGKA | |
| SCHEMBL8945838 | 0.86 | HSP90AA1 (0.55) | CNR2TRPV1POLBPOLA1DGKA | |
| SCHEMBL17178187 | 0.85 | ALDH1A1 (0.38) | CNR2LMNAMEN1KMT2ACYP1A2 | |
| SCHEMBL15773178 | 0.85 | ALDH1A1 (0.38) | CNR2LMNAMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100714-A1 | CELL PENETRATING CYANINE-COUPLED ANTIBODIES | CITY OF HOPE (US) | 2017-06-15 | — | — | WO | disclosed |