Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 19/20 | 0.67 |
| ▸ | ACE | P12821 | 4/20 | 0.67 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17980263 | 1.00 | MME (0.67) | MMEACEMMEL1 | |
| SCHEMBL17968665 | 1.00 | MME (0.67) | MMEACEMMEL1 | |
| SCHEMBL14890607 | 0.92 | MME (0.79) | MMEACEMMEL1 | |
| SCHEMBL22331066 | 0.92 | MME (0.79) | MMEACEMMEL1 | |
| SCHEMBL16241271 | 0.92 | MME (0.79) | MMEACEMMEL1 | |
| SCHEMBL19705947 | 0.92 | MME (0.79) | MMEACEMMEL1 | |
| SCHEMBL17968666 | 0.88 | MME (0.52) | MMEACEMMEL1 | |
| SCHEMBL17968663 | 0.87 | MME (0.64) | MMEACEMMEL1 | |
| SCHEMBL17980206 | 0.87 | MME (0.64) | MMEACEMMEL1 | |
| SCHEMBL19705880 | 0.87 | MME (0.64) | MMEACEMMEL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9682052-B2 | Neprilysin inhibitors | THERAVANCE BIOPHARMA R&D IP, LLC (US) | 2017-06-20 | — | — | US | disclosed |