Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2479171 | 0.89 | GABRR1 (0.35) | GABRR1GABBR2GABBR1 | |
| SCHEMBL640718 | 0.80 | GABRR1 (0.39) | GABRR1GABBR2GABBR1 | |
| SCHEMBL27442263 | 0.79 | GABRR1 (0.32) | GABRR1GABBR2GABBR1 | |
| SCHEMBL18790926 | 0.78 | TSHR (0.33) | — | |
| SCHEMBL23194400 | 0.77 | METAP1 (0.31) | GABRR1GABBR2GABBR1 | |
| SCHEMBL25020156 | 0.75 | GABRR1 (0.30) | GABRR1 | |
| SCHEMBL16297525 | 0.75 | — | — | |
| SCHEMBL24482509 | 0.75 | — | — | |
| SCHEMBL17918959 | 0.75 | — | — | |
| SCHEMBL8692735 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170165500-A1 | ADVANCED ROTATING-SHIELD BRACHYTHERAPY AND PLANNING OF THE SAME | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2017-06-15 | — | — | US | disclosed |