Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRR1 | P24046 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27442263 | 0.85 | GABRR1 (0.32) | GABRR1 | |
| SCHEMBL25472821 | 0.77 | GABBR2 (0.36) | GABRR1 | |
| SCHEMBL16297584 | 0.76 | — | — | |
| SCHEMBL3366284 | 0.76 | — | — | |
| SCHEMBL18965474 | 0.75 | GABRR1 (0.32) | GABRR1 | |
| SCHEMBL23194400 | 0.73 | METAP1 (0.31) | GABRR1 | |
| SCHEMBL18532308 | 0.71 | ALDH1A1 (0.38) | — | |
| SCHEMBL24482509 | 0.71 | — | — | |
| SCHEMBL16297525 | 0.71 | — | — | |
| SCHEMBL8692735 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3045206-B2 | POLYCYCLIC CARBAMOYLPYRIDONE DERIVATIVE HAVING HIV INTEGRASE INHIBITORY ACTIVITY | VIIV HEALTHCARE CO (US) | 2023-02-15 | — | — | EP | disclosed |