Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.41 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19224309 | 0.93 | ADORA3 (0.39) | ADORA3P2RY12ADORA2BADORA1ADORA2A | |
| SCHEMBL19224315 | 0.92 | ADORA3 (0.38) | ADORA3P2RY12ADORA2BADORA1ADORA2A | |
| SCHEMBL12023022 | 0.88 | ADORA3 (0.40) | ADORA3P2RY12ADORA2BADORA1 | |
| SCHEMBL12023073 | 0.87 | ADORA3 (0.39) | ADORA3P2RY12ADORA2BADORA1 | |
| SCHEMBL18776426 | 0.82 | ADORA3 (0.43) | ADORA3P2RY12ADORA2BADORA1 | |
| SCHEMBL18776436 | 0.82 | ADORA3 (0.40) | ADORA3ADORA2BADORA1ADORA2ATSHR | |
| SCHEMBL19224637 | 0.81 | MEN1 (0.41) | ADORA3ADORA1MEN1KMT2APRKAG1 | |
| SCHEMBL18776432 | 0.81 | ADORA3 (0.40) | ADORA3P2RY12ADORA2BADORA1ADORA2A | |
| SCHEMBL19225103 | 0.81 | MEN1 (0.41) | ADORA3ADORA1MEN1KMT2APRKAG1 | |
| SCHEMBL19224639 | 0.80 | MEN1 (0.40) | ADORA3ADORA1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100461-A1 | POLYNUCLEOTIDE CONSTRUCTS HAVING AN AUXILIARY MOIETY NON-BIOREVERSIBLY LINKED TO AN INTERNUCLEOSIDE PHOSPHATE OR PHOSPHOROTHIOATE | SOLSTICE BIOLOGICS, LTD. (IE) | 2017-06-15 | — | — | WO | disclosed |