SCHEMBL18965754

SCHEMBL18965754

Cc1cc2ccc3cc(N)sc3c2s1

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.36
ALDH1A1 P00352 2/20 0.31
MAPT P10636 2/20 0.31
NPC1 O15118 1/20 0.31
GFER P55789 1/20 0.31
HSD17B10 Q99714 1/20 0.31
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18965673 0.90 BACE1 (0.33) BACE1ALDH1A1MAPTNPC1GFER
SCHEMBL18888092 0.88 BACE1 (0.33) BACE1ALDH1A1HSD17B10GAA
SCHEMBL18544444 0.88 BACE1 (0.33) BACE1ALDH1A1MAPTNPC1GFER
SCHEMBL20230864 0.88 BACE1 (0.33) BACE1ALDH1A1MAPTNPC1GFER
SCHEMBL4420846 0.86 CYP2A6 (0.36) ALDH1A1MAPT
SCHEMBL4420026 0.86 BACE1 (0.39) BACE1ALDH1A1HSD17B10
SCHEMBL4420535 0.77 BACE1 (0.47) BACE1
SCHEMBL18195307 0.76 ALDH1A1 (0.31) ALDH1A1MAPT
SCHEMBL17934681 0.75 BACE1 (0.35) BACE1ALDH1A1MAPTHSD17B10GAA
SCHEMBL10441966 0.75 ALDH1A1 (0.33) ALDH1A1NPC1HSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3551635-B1 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2021-04-28 EP disclosed
EP-3166949-B1 THIENOTHIOPHENE-ISOINDIGO CLAP CO LTD (KR) 2021-02-17 EP disclosed
WO-2020078815-A1 INDACENO DERIVATIVES AS ORGANIC SEMICONDUCTORS BASF SE (DE) 2020-04-23 WO disclosed
EP-3386989-B1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2019-10-23 EP disclosed
WO-2018104367-A2 THIENO-INDENO-MONOMERS AND POLYMERS BASF SE (DE) 2018-06-14 WO disclosed
WO-2017097924-A1 NAPHTHOINDACENODITHIOPHENES AND POLYMERS BASF SE (DE) 2017-06-15 WO disclosed