Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18966537 | 0.96 | NAMPT (0.34) | NAMPT | |
| SCHEMBL18966535 | 0.94 | NAMPT (0.33) | NAMPT | |
| SCHEMBL18957181 | 0.94 | NAMPT (0.32) | MTNR1AMTNR1BNAMPTTDP1L3MBTL1 | |
| SCHEMBL18957183 | 0.94 | NAMPT (0.32) | MTNR1AMTNR1BNAMPTTDP1L3MBTL1 | |
| SCHEMBL18966645 | 0.93 | NAMPT (0.32) | NAMPT | |
| SCHEMBL18966611 | 0.92 | NAMPT (0.32) | NAMPT | |
| SCHEMBL21539512 | 0.92 | NAMPT (0.32) | NAMPT | |
| SCHEMBL18966996 | 0.92 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| SCHEMBL18966545 | 0.91 | NAMPT (0.33) | NAMPT | |
| SCHEMBL18966680 | 0.91 | NAMPT (0.32) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017100537-A1 | BETA-LACTAMASE INHIBITORS | VenatoRx Pharmaceuticals, Inc. (US) | 2017-06-15 | — | — | WO | disclosed |