Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.41 |
| ▸ | APEX1 | P27695 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | PGR | P06401 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16271549 | 0.94 | THRB (0.41) | THRBTSHRCHRM1CHRM3CHRM5 | |
| SCHEMBL2277551 | 0.86 | THRB (0.46) | THRBTSHRCHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL1904155 | 0.86 | THRB (0.46) | THRBTSHRCHRM1CHRM3CHRM5 | |
| SCHEMBL15830114 | 0.84 | THRB (0.44) | THRBTSHRCHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL32674543 | 0.84 | THRB (0.44) | THRBTSHRCHRM1CHRM3CHRM5 | |
| SCHEMBL1898858 | 0.84 | THRB (0.47) | THRBTSHRCHRM1CHRM3CHRM5 | |
| SCHEMBL1597440 | 0.81 | THRB (0.53) | THRBTSHRCHRM1CHRM3CHRM5 | |
| Hydrochloric Acid SCHEMBL475669 | 0.81 | THRB (0.53) | THRBTSHRCHRM1CHRM3CHRM5 | |
| Betaine SCHEMBL6062726 | 0.81 | APEX1 (0.48) | THRBTSHRCHRM1CHRM3CHRM5 | |
| SCHEMBL344298 | 0.80 | TSHR (0.55) | THRBTSHRCHRM1CHRM3CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014095754-A1 | FILTRATION SYSTEMS AND MEMBRANES WITH ENHANCED FLUX AND METHOD FOR THEIR PREPARATION | BASF SE (DE) | 2014-06-26 | — | — | WO | disclosed |
| WO-2014095753-A1 | MEMBRANES WITH IMPROVED FLUX AND METHOD FOR THEIR PREPARATION | BASF SE (DE) | 2014-06-26 | — | — | WO | disclosed |
| EP-2496550-A2 | CROSSLINKED ZWITTERIONIC HYDROGELS | University Of Washington Through Its Center For Commercialization (US) | 2012-09-12 | — | — | EP | disclosed |
| WO-2011057219-A2 | CROSSLINKED ZWITTERIONIC HYDROGELS | UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2011-05-12 | — | — | WO | disclosed |