Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 6/20 | 0.31 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | TEK | Q02763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18975969 | 0.90 | TP53 (0.49) | TP53LMNAGAAWEE1CHEK1 | |
| SCHEMBL18328995 | 0.87 | TP53 (0.40) | TP53LMNAGAAWEE1CHEK1 | |
| SCHEMBL12608686 | 0.86 | WEE1 (0.44) | TP53WEE1CHEK1 | |
| SCHEMBL15848976 | 0.86 | TP53 (0.39) | TP53WEE1 | |
| SCHEMBL15848980 | 0.81 | TP53 (0.63) | TP53 | |
| SCHEMBL2361050 | 0.77 | TP53 (0.47) | TP53WEE1CHEK1 | |
| SCHEMBL16131566 | 0.77 | TP53 (0.51) | TP53LMNAWEE1CHEK1KDR | |
| SCHEMBL12608670 | 0.76 | WEE1 (0.41) | TP53WEE1CHEK1KDR | |
| SCHEMBL13418915 | 0.76 | TP53 (0.49) | TP53WEE1KDRTEK | |
| SCHEMBL18329003 | 0.76 | TP53 (0.40) | TP53LMNAKDRTEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170165229-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | INCURON, INC. | 2017-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170165229-A1 | CARBAZOLE COMPOUNDS AND THERAPEUTIC USES OF THE COMPOUNDS | MALT1, PAICS, BCL9 | TP53 28/4885LMNA 4194/4885GAA 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.