SCHEMBL1896964

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL20614382	0.89	LMNA (0.49)	PIK3CAALDH1A1CYP1A2CYP2C9CYP2C19
	SCHEMBL1897045	0.82	PIK3CA (0.70)	PIK3CAALDH1A1GAAKDM4EGLA
	SCHEMBL1900972	0.80	LMNA (0.50)	ALDH1A1GAACYP1A2CYP2C9CYP2C19
	SCHEMBL13439818	0.79	PIK3CA (0.53)	PIK3CAALDH1A1KDM4EPIK3CDPIK3CB
	SCHEMBL1984787	0.78	PIK3CA (0.53)	PIK3CAALDH1A1KDM4EHPGDHSD17B10
	SCHEMBL1899475	0.78	PIK3CA (0.48)	PIK3CACYP1A2CYP2C9CYP2C19LMNA
	SCHEMBL14548263	0.78	CYP1A2 (0.45)	ALDH1A1CYP1A2CYP2C9CYP2C19LMNA
	SCHEMBL1987016	0.77	PIK3CA (1.00)	PIK3CAALDH1A1GAAKDM4EGLA
	SCHEMBL12676394	0.77	PIK3CA (0.46)	PIK3CACYP1A2CYP2C9CYP2C19LMNA
	SCHEMBL1985054	0.76	PIK3CA (0.52)	PIK3CAPIK3CDPIK3CBMTORPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.