SCHEMBL18969686

SCHEMBL18969686

COCc1cc(C2(c3ccccc3)c3ccccc3Oc3ccccc32)cc(C)c1O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35
PDK2 Q15119 1/20 0.31
PDE4D Q08499 1/20 0.31
PRKCE Q02156 3/20 0.31
MYLK Q15746 2/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PRKCG P05129 1/20 0.31
MAPT P10636 1/20 0.31
PRKCA P17252 1/20 0.31
APEX1 P27695 1/20 0.31
RECQL P46063 1/20 0.31
KMT2A Q03164 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27428804 0.86 ESR1 (0.50) ESR1ESR2PDK2PDE4DPRKCE
SCHEMBL19421343 0.84 ESR1 (0.36) ESR1ESR2MAPT
SCHEMBL18100879 0.82 ESR1 (0.54) ESR1ESR2PDK2PDE4DPRKCE
SCHEMBL18100873 0.77
SCHEMBL18100891 0.75 ESR1 (0.46) ESR1ESR2PDK2PDE4DPRKCE
SCHEMBL10076748 0.74 ESR1 (0.50) ESR1ESR2PDK2PDE4DPRKCE
SCHEMBL31276040 0.73 PDK2 (0.39) ESR1ESR2PDK2PRKCEMEN1
SCHEMBL27778052 0.72 CHRM2 (0.45) ESR1ESR2MEN1ALDH1A1MAPT
SCHEMBL4388225 0.72 ALOX5 (0.41) MEN1MAPTKMT2A
SCHEMBL18100888 0.71 ESR1 (0.40) ESR1ESR2PDK2PDE4DMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170168395-A1 ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, MASK BLANK PROVIDED WITH ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2017-06-15 US disclosed
US-20170168395-A1 ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE RESIN COMPOSITION, ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, MASK BLANK PROVIDED WITH ACTIVE LIGHT SENSITIVE OR RADIATION SENSITIVE FILM, PATTERN FORMING METHOD, METHOD FOR MANUFACTURING ELECTRONIC DEVICE, AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2017-06-15 US disclosed