Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14059147 | 0.89 | TBK1 (0.80) | TBK1IKBKE | |
| SCHEMBL14059077 | 0.89 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL14059490 | 0.88 | TBK1 (0.79) | TBK1IKBKE | |
| SCHEMBL14059034 | 0.88 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL14059709 | 0.87 | TBK1 (0.87) | TBK1IKBKE | |
| SCHEMBL14058915 | 0.87 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL14059372 | 0.86 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL14059234 | 0.85 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL14059191 | 0.85 | TBK1 (1.00) | TBK1IKBKE | |
| SCHEMBL14059219 | 0.82 | TBK1 (1.00) | TBK1IKBKE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714668-B9 | THIAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2017-06-14 | — | — | EP | disclosed |