Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567271 | 0.90 | TSHR (0.54) | TSHRALDH1A1HSD17B10LMNAEPHX2 | |
| SCHEMBL18641686 | 0.90 | TSHR (0.54) | TSHRALDH1A1HSD17B10LMNAEPHX2 | |
| SCHEMBL23132220 | 0.90 | TSHR (0.54) | TSHRALDH1A1HSD17B10LMNAEPHX2 | |
| SCHEMBL19032585 | 0.89 | DGKA (0.61) | DGKAKDM4EEPHX2PRSS1PRSS2 | |
| SCHEMBL24573010 | 0.89 | DGKA (0.61) | DGKAKDM4EEPHX2PRSS1PRSS2 | |
| SCHEMBL31036510 | 0.89 | DGKA (0.61) | DGKAKDM4EEPHX2PRSS1PRSS2 | |
| SCHEMBL24573593 | 0.89 | DGKA (0.61) | DGKAKDM4EEPHX2PRSS1PRSS2 | |
| SCHEMBL24587794 | 0.89 | DGKA (0.61) | DGKAKDM4EEPHX2PRSS1PRSS2 | |
| SCHEMBL25342695 | 0.89 | DGKA (0.61) | DGKAKDM4EEPHX2PRSS1PRSS2 | |
| SCHEMBL25341615 | 0.89 | DGKA (0.61) | DGKAKDM4EEPHX2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017099823-A1 | COMPOSITIONS AND METHODS FOR DELIVERY OF THERAPEUTIC AGENTS | MODERNATX, INC. (US) | 2017-06-15 | — | — | WO | disclosed |