Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22513741 | 0.81 | TSHR (0.36) | TSHR | |
| SCHEMBL25804905 | 0.78 | — | — | |
| SCHEMBL3822152 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL269067 | 0.74 | TSHR (0.37) | TSHR | |
| SCHEMBL3822154 | 0.74 | ALDH1A1 (0.31) | — | |
| SCHEMBL270183 | 0.74 | TSHR (0.37) | TSHR | |
| SCHEMBL6398021 | 0.69 | — | — | |
| SCHEMBL5682440 | 0.69 | — | — | |
| SCHEMBL5949174 | 0.69 | TSHR (0.46) | TSHR | |
| SCHEMBL20055681 | 0.68 | ACE2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017097728-A1 | BRIDGED PIPERIDINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2017-06-15 | — | — | WO | disclosed |