Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.45 |
| ▸ | ACACA | Q13085 | 11/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.35 |
| ▸ | MST1R | Q04912 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18971929 | 0.90 | SLC6A3 (0.37) | ACACBACACASLC6A3TP53MAPT | |
| SCHEMBL18971288 | 0.84 | ACACB (0.47) | ACACBACACASLC6A3JAK2NTRK1 | |
| SCHEMBL12115750 | 0.84 | ACACB (0.47) | ACACBACACASLC6A3JAK2NTRK1 | |
| SCHEMBL15099566 | 0.84 | ACACB (0.47) | ACACBACACASLC6A3JAK2NTRK1 | |
| SCHEMBL18971142 | 0.84 | ACACB (0.47) | ACACBACACASLC6A3JAK2NTRK1 | |
| SCHEMBL12115813 | 0.78 | ACACB (0.39) | ACACBACACASLC6A3 | |
| SCHEMBL18971333 | 0.78 | ACACB (0.39) | ACACBACACASLC6A3 | |
| SCHEMBL18971252 | 0.77 | ABL1 (0.41) | ACACBACACASLC6A3ABL1 | |
| SCHEMBL12115868 | 0.77 | ABL1 (0.41) | ACACBACACASLC6A3ABL1 | |
| SCHEMBL12115879 | 0.76 | ACACB (0.40) | ACACBACACASLC6A3ABL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2155645-B1 | HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS | SYNGENTA LTD (GB) | 2017-06-14 | — | — | EP | disclosed |